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  ű ǰ, ǰ ǰ : DLTXR500, DAGO25, DR-AZFLT  ۼ

					

					


HL 20-04
 

ǰ

 

ű ǰ, ǰ ǰ ׿ ˷帮 ῡ Ͻñ ٶϴ.

 

113.

Levetiracetam

DLTXR500 500mg/Tab Keppra XR(UCB) (113)
DLTXR750 750mg/Tab Keppra XR(UCB) (113)

[] ô óܹ(SV2A) Ͽ GABA/glycine ü allosteric modulator ȿ ϰ high voltage activated Ca2+channel Ͽ װȿ Ÿ.

[ȿ] ΰ(12 ̻) : 1 ġ ϰ ʴ 2 ϰų ʴ κй ġ.

[] 50kg ̻ 12 ̻ ûҳ : ʱ 1 1ȸ 1,000mg, Ļ . 2~4ָ 1 1ȸ 1,000mg Ȥ (Max. 3,000mg/day). ȯ : CLcr 50~79ml/min/1.731,000~2,000mg, qd. CLcr 30~49ml/min/1.73500~1500mg, qd. CLcr 30ml/min/1.73 ̸ - 500~1,000mg, qd.

[] ڻ浿, ڻൿ, , , , Ƿ, , , ൿ̻, , Ҹ, Ű, εο, , , , , , ȭҷ, Ŀ, ħ, ÷翣, ˾, , ȣ.

[ݱ] Ǵ ǷѸ ü ι ȯ.

[] ڻ浿 Ǵ ڻൿ, Ǵ ȭ а ൿ ȭ ͸. ȯڴ 뷮 ű ˻ (CLcr 60ml/min/1.73 ̸ 50% ). (ȣ߱, , , ǰ, ) . ߴ . м Ұ.

[Ӻ] FDA C, Ӻαݱ 2.

[] DUR [] Max. 3,000mg/day, []  

 

117. ŽŰ

Agomelatine

DAGO25 25mg/Tab Argotin(ȯ) (117)

[] ü MT1, MT2 ۿ ֱ⸮ ȭ ֿ ǰ 5-HT2C ü ۿ ׿ ۿ Ÿ.

[ȿ] ֿ .

[] 1 1ȸ 1, ħ . ġ 2 , 1 1ȸ 2 (Max. 50mg/day).

[] , , , Ҿ, , , Ҹ, , , , , , Ƿ, ü, ALTAST , ݼ, Ǹ, ̻, Ҿı, , 帰 þ, ̸, , , , ε巯, ü߰, ڻ, ڻൿ, , , , ȥ, GGT .

[ݱ] ࿡ ִ ȯ, ȯ, Ʈƹ̳ ġ 3踦 ʰϴ , CYP1A2 (÷纹, ÷ϻ ) , ҳ ȯ.

[] ġ , 3, 6, 12, 24(ġ 󵵷) ˻ ǽ. ջ /¡, ġ ġ 3踦 ʰϴ ߴ. , ü߰, ݼ 氣, , ջ ִ ȯ ջ ๰ . ȭ, ڻ ൿ/, ൿ ȭ ͸. Ʈΰ, (ߵ CYP1A2 ), ǽ (CYP1A2 ) . 18 ̸ ҾƳ 75 ̻ ڿ ȿ Ȯ.

[Ӻ] ADEC B1.

[] DUR [ݱ] ciprofloxacin(DW-CF200J, DW-CF400J, DW-CF250, DW-CF500), fluvoxamine(DFVOX100, DFVOX50).  

 

132. ̺

Dylastine Nasal Spray

DR-AZFLT (1BTL=120ȸ) 1Puff Azelastine HCl 0.137mg, Fluticasone propionate 0.05mg(α) (132)

[] Azelastine : H1-ü Ÿ, Ʈ ˷ Ű к . Fluticasone propionate : ڸƼڽ׷̵ ׿ ۿ.

[ȿ] ߵ Ǵ ˷⼺ ġ.

[] 6 ̻ Ҿ : 1 2ȸ, 1ȸ й.

[] , , ̰̻( ), , (ڱذ, , ), ä, , ħ, , ڱ.

[ݱ] , 6 ̸ Ҿ, ֱ ܰ ޾Ұų ġ ȯ, Ӻ .

[] , , , ż ̷, , ȱ ܼ, ȯ. þ ȭ, ȳ , , . Ҿ ûҳ⿡ ͸. , ںýŸƮ Ǿǰ CYP3A4 . ڱ Ǵ (ڴȭ ). ȸ ⸦ 6ȸ л . 7 ̻ 쿡 ̸ 1ȸ л . ù 6 ̳ . ǿº(8 ).

[Ӻ] FDA C, Ӻαݱ 2.

[] DR-CICL(: LCICN) ü.

 

214. а

Edarbyclor

DAZCH12.5 1 Azilsartan medoxomil 40mg, Chlorthalidone 12.5mg(ɴ) (214)
DAZCH25 1 Azilsartan medoxomil 40mg, Chlorthalidone 25mg(ɴ) (214)

[] Azilsartan : Angiotensin II Receptor Blocker(ARB). Chlorthalidone : Thiazide ̴.

[ȿ] 縣ź޵ҹ ܵ ϰ ʴ ¼ . 2 ȯڿ ġ ǥ п ϱ ʿ ȯ ʱ .

[] ȸ 1 1ȸ 40/12.5mg(1), Ļ . 2~4 ʿ 1 1ȸ 40/25mg(1) (Max. 40/25mg/day).

[] ũƼ , , , , , , ٰ, Ƿ, , , Į, Į , Ʈ, dz, ǽ, ̻, , , , .

[ݱ] Ǵ Ƽ, ƹ̵ ü ִ ȯ, , Į, (eGFR < 30ml/min/1.73), Ʈ, Į, ִ , ġ ֵı, Ƭ ȯ, 索 Ǵ ߵ ȯڿ ˸Ű , Ӻ, .

[] ջ, ༺ ȯ ȯڿ ȥ . ȯڿ . ҵǰų ȿ׷ ɼ ִ ȯ(, , 뷮 ̴ ) ׷ . ű -ٽ-˵׷а(RAAS) Ȱ ȯ, ŵ , ̽, û ұ, , ߼ ˵׷, 뵿 ¸ , ⼺ ɱٺ, ΰ , Ű , ȭ, ȭ, dz, 索 ȯ, . Ż, ڸƼڽ׷̵, νڱȣ ȯ, ѿ ȯ. м Ұ, Ƿ PTP ״ , .

[Ӻ] FDA D, Ӻαݱ 2.

[] DJCVDL12.5(: BCVA) ü.

 

232. ȭ˾

Esoduo

DESOSB 1 Esomeprazole 20mg, Sodium bicarbonate 800mg(ٴ) (232)

[] Esomeprazole : (PPI, proton pump inhibitor)μ H+/K+-ATPase Ͽ к . Sodium bicarbonate : Į ๰μ ȭ 굵 ҽŴ.

[ȿ] ĵ ȯ(GERD) : ĵ ȯ ߹ Ⱓ , ĵ ĵ ȯ ġ.

[] : 1 1ȸ 1(20/800mg), 1ð() .

[] , , , , ظ, , , , Ҹ, , ̻, , , ȿ , Ǻο, , , ε巯, , .

[ݱ] ̴̹ , Ÿڳ dz, Ǻ ȯ, ɱٰ շ(L-Ƹ ), .

[] , ȭ˾, , , , Ŭθī, ı, Į, Į, - , Ʈ ʿ ϴ ȯ, . ŬνƮ ǽǷռ , ո ô , ׳׽, Ǻ ȫݷǪ, ī(, , , Ż), ߻ . û ũθ׶ A(CgA) ˻ ּ 14 Ͻ ߴ(Ű泻к ܰ˻ 缺 ). 굵 ޴ ๰(Ʈڳ, Ƽ, ), CYP2C19 (, Ż, ̹, , ĸ, ڳ, ǷνŸ ), CYP3A4 (ŬƮθ̽ ), CYP2C19 CYP3A4 (ǽ, ƮƮ), Ŭǵ׷, ƮƮ, Ÿũθ, Į . м Ұ.

[Ӻ] FDA C, Ӻ 2.

[] DOMP20(: BOMEZ), DOMP40(: BOMEZB) ü.

 

237.

Biotop high

DBHIGH 1Cap Enterococcus faecalis T-110 30mg, Bacillus mesentericus Toa 150mg, Clostridium butyricum Toa 150mg(ѿù̿ĸ) Ϲ(237) ޿

[] ο ϰ հ Ǵ ȭհ Ϻ~忡 ϰ ر , 忡 ϰ Ƽ ƼƮ Ͽ ر ϸ, Ǵ̳ ٸ ͱ ִ ȯ ϴ յǾ 峻 ȭŴ.

[ȿ] , , , ظ, 峻̻ȿ.

[] 1 3ȸ, 1Cap .

[] 1 Ͽ ߴ.

[ݱ] 7, ҳ ִ ȯ.

[] Ȳ5ȣ(¿ο FCF) ϰų ˷ ִ ȯ.

[Ӻ] Ȯ.

[] DLACI250(: BXLACI) ü.

 

241. ϼüȣ

Growtropin- Inj cartridge

DH-GT20P Somatropin(Recombinant human growth hormone) 20IU/1.8ml SR(ST) (241)

[] DNA Ÿ̵ ȣ IGF-1 ϰ, ȭ, ƹ̳ , ܹ ռ ݰ .

[ȿ] ϼü ȣ кַ Ҿ . Ҿ Ư߼ (ISS). ʰ ü м ͳı Ȯε Ҿ .

[] ϼü ȣ к : 1Ͽ 0.6IU(0.2mg)/kg Ǵ 14.4IU(4.8mg)/, ֻ 5~7ȸ, ֻ 2~4ȸ . Ư߼ : 1Ͽ 1.11IU (0.37mg)/kg, 6~7ȸ SC. ͳı : 0.14IU(0.047mg)/kg/day, SC.

[] , , ֻ , , , AST, ALT, ALP , , , , ߰, 뼺 ̰, ܰ, ΰܺи, α, ߰⿰, , ֱ⼺ , , ̿۷κ , ̰ , , , ս, , 󼱱, , ȣ걸 , ߼ , LDH , ݷ׷ , û , , ܹ鴢, ܹ.

[ݱ] , Ȱ ļ 索 , ļ 索 , Ǽ, ִ ȯ, ϼü ϼ ȣ к Ҹ Ű 翡 , , ټ ܻ Ǵ ޼ ȣ ϴ պ ߴ ޼ ȯ, ޼ ȣ ȯ, , Ӻ .

[] ȯ, , ȣ ͳı к ȯ(ΰܺи ). Ҿƾ ڿ ߻ . ˻ ġ, ͸. ֻ Ÿ Ƿ ֻ ׻ 뷮 Ȯ. ֻ ϱ , , ֻ ٲ㰡 . (2~8). (2~8) 21, ǿº(25 ) 10 ̳ .

[Ӻ] Ӻ 2.

[] DH-GT16J(: IGHO16) ü.

 

316. ȥպŸ(ŸA,D ȥ )

Beecom-C

DVITBC 1 thiamine nitrate 15mg, riboflavin 10mg, pyridoxine hydrochloride 5mg, cyanocobalamin 5µg, ascorbic acid 600mg, calcium pantothenate 23.2mg, nicotinamide 25mg, tocopherol acetate 20IU, selenium 21.6µg(Ѿ) Ϲ(316) ޿

[] Thiamine(Vit. B1) : Ű, , ȭ, , Ƿ. Riboflavin(Vit. B2) : , , , , , Ǻο ȭ. Ascorbic acid(Vit. C) : ޺Ǻκ  ħ ȭ, ո, .

[ȿ] üǷ, ӽ, ü, Ÿ B1, B2, B6, C, E .

[] 12 ̻ : 1, 1 2ȸ .

[] κ谨, , , , , , , , Ǻο, ȣ , Ż, .

[ݱ] ࿡ ι ִ ȯ, 12 ̸ .

[] 괢 ȯ, Ӻ, , , ȭ˾, ˾缺忰, Ѽ忰 ȯ ȯ, ȯ , , ܹ, dz, Ἦ ִ ȯ. Ȳ5ȣ(¿ο FCF) ϰų ˷ ִ ȯ. , ȫ ź ϴ Ŀ . λ꿰, Į, 汸 ƮŬ , , .

[Ӻ] Ȯ.

[] DVITACE(: BACE) ü.

 

396.

Jardiance duo

DJDUO500 1 Empagliflozin 12.5mg, Metformin HCl 500mg(ΰ) (396)

DJDUO1G 1 Empagliflozin 12.5mg, Metformin HCl 1,000mg(ΰ) (396)

[] Empagliflozin : SGLT-2 輳 ϽŴ. Metformin : ̿ ̸, Ż .

[ȿ] ı۸÷ Ʈ 2 索 ȯ Ű Ļ  .

[] 1 2ȸ, 1 Ļ Բ (Max. 25/2000mg/day). ȯ : eGFR 45~59ml/min/1.73 - Max. 10mg/1000mg/day. 45ml/min/1.73 ̸ ߴ.

[] , ΰ, ı , , , , , , Ŀ, ̰ ̻, , , , û , ü׷ , ε巯, , ũƼ , 籸ü , 츶ũƮ .

[ݱ] , CrCl 45ml/min ̸ , Ż, , ũ, ޼ɱٰ, , 1, 索 ȥ, ޼ Ҿ ɺ, , ҷ, ϼüɺ, νűɺ, 48ð ̳, 缱 Ƴ ϴ ˻縦 ޴ ȯ, Ӻ, .

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