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  ű ǰ : DC-TFD15, DC-TFD20  ۼ

					

					

HL 20-09

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ű ǰ ˷帮 ῡ Ͻñ ٶϴ.

 

421. ׾Ǽ

Lonsurf

DC-TFD15 1 Trifluridine 15mg, Tipiracil HCl 7.065mg() (421) ޿

DC-TFD20 1 Trifluridine 20mg, Tipiracil HCl 9.42mg() (421) ޿

[] Trifluridine : Thymidine üμ, DNA ռ thymidine ۿϿ DNA ռ ϰ 缼 . Tipiracil : Trifluridine ϴ thymidylic phosphorylase Ͽ trifluridine ü̿ .

[ȿ] ÷Ǹ̵ 迭, 츮öƾ ̸ĭ ⺻ ϴ ׾ ȭ ġḦ ְ, VEGF ġ, EGFR ġ(RAS ) ġḦ ְų ġ ̼ ȯ ġ.

[] ʱ Ʈ÷縮 35mg//ȸ, 1 2ȸ 1ð ̳ (Max. Ʈ÷縮 80mg/ȸ). 5ϰ 2 ޾ 2 ݺ 14ϰ ޾ ϴ 1 cycle ϰ, ϰų ߻ ݺ . ༺ ִ 3ȸ ϸ, (Min. 20mg//ȸ). ȣ߱ 0.5109/L ̸, Ǽ 50109/L ̸, ߿ȣ߱ ߻ Ͻ ߴϸ, ȸ Ͽ 簳.

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[ݱ] ࿡ ɰ ִ ȯ, Ӻ, , ҳ, Ǵ , ߵ~ ȯ, Ҿ.

[] ȯ, ȯ, ~ߵ ȯ, . ġ ֱ 15° ˻ , ġ ġ ˻(dipstick urinalysis) ܹ鴢 ͸ . ÷Ǹ̵ 迭 ׾Ǽ, ƮװǪ , Ʈ÷ο , (÷), (ƮƮ, Ʈõ) ɰ ߻ . ε thymidine kinase . . м Ұ.

[Ӻ] Ӻ ݱ.

 


2020. 04. 27.
 

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