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HL 19-74

 

ǰ


ű ǰ ǰ ˷帮 ῡ Ͻñ ٶϴ.

 

421. ׾Ǽ

Nanoliposomal irinotecan

ALIRTC 43.3mg(Irinotecan hydrochloride 50mg)/10ml Vial Onivyde() (421) ޿

[] Irinotecan sucrosofate · Ե Irinotecan Ȱ ü SN-38 topoisomerase I ϰ DNA S-phase ۿϿ DNA .

[ȿ] Ÿ ϴ ׾Ͽ ȯڿ ÷ο ں ̼ ġ.

[] μ 70mg/m 5% ֻ Ǵ 0.9% ȭƮ ֻ 500ml Ͽ, 2ָ 90а IV infusion. ÷ο ں . UGT1A1*28 븳ڿ ü ȯ : 50mg/m, 90а IV infusion. ֱ 70mg/m . 3, 4 ̻ , 1 Ϸ ȸǸ 50mg/m2(1), 2 ̻ 43mg/m2, 3 ̻̳ ȯ, Ƴʶý ߻ ߴ. ( 1 ) ̵ , Ʈ 0.25mg~1mg, IV/SC. 30 ڸƼڽ׷̵ ױ óġ.

[] , Ƿ, , , , Ŀ尨, , ߿, , ȣ߱, , Ż, ũ, , ޼ ź, ǰ, ü߰, Ż, Թ, , ALT, ˺ι, ׳׽, Į, Į, λ, ũƼ .

[ݱ] ּ̳ ִ ȯ.

[] ߿ ȣ߱, ȣ߱Ҽ ߻ . ֱ ͸, ANC 1500/mm3 Ǵ ߿ ȣ߱ . ߻ , ȯڿ . ȯ ߻ . ȣ, ħ, ߿, ȯ ȯ . Ȯ ¡Ŀ ͸. CYP3A4 (ġ 2 ߴ), CYP3A4 (ġ 1 ߴ), Ǵ UGT1A1 . ӱ 1, 4 ӹ . ̸ĭ꿰 ü . , ǿ 4ð ̳, (2~8) 24ð ̳ . ζ . к, (2~8) .

[Ӻ] FDA D, Ӻ 2.

[] [ݱ] BATVRA, BATVRB, BICON, YICON.


ǰ

ڵ

Է

ǰ
(ȸ)

ǽ

IDYSPO

Clostridium botulinum toxin type A 500unit/Vial

Dysport
(Լڸ)

Ͻǰ
ü : IBOTOX, ICTOX, IBTX25



IDYS

Clostridium botulinum toxin type A 20unit

 

 

  

   

2020. 02. 21.

    ǰ ( 9561)