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  ű ǰ ǰ : BPRM37, TLP, BBAR2, IIKMAB  ۼ

					

					

HL 19-47 

ǰ

ű ǰ ǰ ˷帮 ῡ Ͻñ ٶϴ.

119. Ÿ ߽Ű

Pramipexole 2HCl monohydrate

BPRM37 0.375mg/Tab Prapexole ER() (119)

[] D2 ü ȿɾ. D3 ü ģȭ .

[ȿ] Ư߼ Ų : ʱ Ų ȯ ġῡ ܵ, Ŀ Ų ȯ .

[] 1 1ȸ, Ļ ð . 0.375mg/day 5~7ϸ (Max. 4.5mg/day). ű ȯ : CrCl 30~50ml/min - ʱ 2 1ȸ 0.375mg(Max. 2.25mg/day), CrCl<30ml/min - Pramipexole Ϲ . ߴ : 10.75mg ҵ 0.75mg/day , 0.375mg/day .

[] , , , Ҹ, , , ȯ, ü , ̻, üܷ ı, , ȥ, , , , , , , Ǹ, .

[ݱ] ࿡ ȯ.

[] ű ȯ, ȯ. ۽ ߻, , ⸳ п ͸ . øƼ, ƸŸ(Ĺ ڱ ͸ 뷮 ), , ڿ( ۿ), Ű̿, Ŭ̵( ۿ) . ź ๰ . м Ұ. .

[Ӻ] FDA C, Ӻ 2.

[] [ݱ] BAMS10, BAMS40(ۿ).

 

131. Ȱ

Latanoprost

TLP 10g/0.2ml Tu Xalost S eye drops() (131)

[] Prostaglandin F2- üμ prostanoid FP ü ۿϿ ȹ Ű Ⱦ .

[ȿ] : 氢 쳻, Ⱒ 쳻, Ⱦ Ⱦϰ. Ҿ : , Ⱦ Ⱦϰ.

[] 1 1ȸ 1, (Max. 1ȸ/day).

[] þ 帲, ڱ, ȱ, ȫäҰħ, 󰢸, ȱ, к , ȱ, Ǯ ȫ, ڸ, ν, , εο, ÷翣, , , , ˷ Ǻι, .

[ݱ] ࿡ ִ ȯ.

[] Żõ 쳻, ȿ(ȫä, ), ü, ü ĸ ΰü, Ȳݺ ڸ ȯ, , , õ ȯ . ȫä, ħ , Ӵ ħ . ٸ Ⱦ 5 ̻ ð ΰ . Ʈ , 15 . Ӻ , 1 ̸ Ҿƿ Ȯ. ȸ ǰ( , ). , ˷̴ Ŀġ ǿ(25 ) 28ϳ .

[Ӻ] FDA C, ADEC B3.

 

142. ڰݿ(Ư̼ 鿪)

Baricitinib

BBAR2 2mg/Tab Olumiant() (142)

BBAR4 4mg/Tab Olumiant() (142)

[] Janus kinase inhibitorμ, JAK1 JAK2 ȿ Ȱ κ Ͽ STAT λȭ Ȱȭ ҽŴν 鿪 Ȱ ϽŴ.

[ȿ] ϳ ̻ ׷Ƽ(DMARDs) ʰų ༺ ߵ~ Ȱ Ƽ ġῡ ܵ Ǵ MTX .

[] 1 1ȸ 4mg, Ļ . 75 ̻ , Ǵ ߼ , ȯ(CrCl 30~60mL/min), ̿ ü3(OAT3) ȯ : 1 1ȸ 2mg.

[] , ݷ׷, , ܼ, , , , , ALT , ȣ߱, ߼, AST , , ü , CPK .

[ݱ] , Ȱ , Ȱ , (CrCl<30mL/min), ANC<1,000 cells/mm3, ALC<500cells/mm3, Hb<8g/dL ȯ, Ӻ, .

[] ǽɵǴ ȯ, , 鿪 ȭ ȯ, , Խ, ȣ߱ , , ۷κ , ~ߵ , , , ִ ȯ . ׷Ƽ(DMARDs), ٸ JAK . (Ƽ, Ÿũθ, Ŭν) . ߻, ̷ Ȱȭ, , μ ջ, , Ǽ ߻ . ẹ ġ. Ǵ ġ Ⱓ , ൶ȭ . 12 ͸. ġⰣ 1 ȿ ӹ .

[Ӻ] Ӻαݱ 2.


Ixekizumab

IIKMAB 80mg/ml PFS Taltz PFS() (142)

[] 鿪 ϸ ǻ Ǽ ߻ ٽ ϴ IL-17A ϴ Ŭüμ, IL-17A ü ȣۿ Ͽ cytokine chemokine .

[ȿ] ǻ Ǽ : Ǵ ġ ʿ ϴ ߵ~ ǻ Ǽ ġ. Ǽ : DMARDs ʰų, ༺ Ȱ Ǽ ȯڿ ܵ Ǵ ٸ DMARDs .

[] ǻ Ǽ, ߵ~ ǻ Ǽ Ǽ : 160mg SC, 2, 4, 6, 8, 10, 12ֿ 80mg SC, 4ָ 80mg SC. Ǽ : 160mg SC, 4ָ 80mg SC. ǿ¿ 30а ġ , ֻ Ǽ ħ , , ֻ. ġ 16~20 Ŀ Ÿ ʴ ߴ .

[] , ֻ , , ܼ, ε , , ÷翣, , ĭ, , , ȣ߱, ǰ, , ε巯, , .

[ݱ] ࿡ μ ȯ.

[] Ȱ ִ ȯ. , ɰ ι, ȯ . ẹ ġ. ġ Ⱓ . (2~8C) . ǿ(30C ) ִ 5ϰ ǰ ڿ Ͽ ( ȵ).

[Ӻ] Ӻαݱ 2.


Tofacitinib

BTOFA10 10mg(Tofacitinib citrate 16.155mg)/Tab Xeljanz(ȭ) (142)

[] 鿪 ڱϴ ȿ JAK(Janus Associated Kinase) . ī Ʈũ ߽ ϴ ȣ (JAK-STATs) Ͽ 鿪 Ȱ ϽŴ.

[ȿ] ڸƼڽ׷̵, Ƽ, 6-޸İǪ(6-MP) ġ Ǵ ʰų, ҽǵǰų Ǵ ༺ ߵ~ Ȱ ˾缺 忰 ġ.

[] 10mg 1 2ȸ, ּ 8 , ġ 5mg Ǵ 10mg 1 2ȸ, Ļ . 10mg 1 2ȸ, 16ְ Ŀ ġ ͼ ߴ. ߵ ź, ߵ ȯ, CYP3A4 , ߵ CYP3A4 CYP2C19 : 10mg 1 2ȸ 5mg 1 2ȸ, 5mg 1 2ȸ 5mg 1 1ȸ . ALC<500cells/mm3, ANC<1,000 cells/mm3, Hb<9.0g/dL - . ANC (500~1,000cells/mm3) - 10mg 1 2ȸ 5mg 1 2ȸ , 5mg 1 2ȸ ߴ. ANC ȸ . ALC<500cells/mm3, ANC<500cells/mm3 - ߴ, Hb 2g/dL ʰ Ǵ Hb<8.0g/dL ȸ ñ ߴ.

[] εο, ݷ׷ġ , , , CPK , , , , , ߿, , , .

[ݱ] ࿡ ȯ, ߴ , Ȱ , Ȱ , , ALC< 500cells/mm3, ANC<500cells/mm3, Hb<8g/dL, Ӻ, ҳ.

[] ǽɵǴ ȯ, , 鿪 ȭ ȯ, , Խ, ȣ߱ , , ۷κ , ~ߵ , , . ߴ , ̷ Ȱȭ, Ÿ Ǽ, Ǻξ, õ, ι ߻ . Ƽ Ŭν 鿪 . Ű . ẹ ġ. 4~8 ͸. ġⰣ 뷮 ּ 4ֵ ȿ ӹ .

[Ӻ] Ӻαݱ 2.

 

214. а

Dukarb

BAMFM 1 Amlodipine 5mg, Fimasartan 60mg() (214)

[] Amlodipine : Calcium channel blockers. Fimasartan : Angiotensin receptor antagonist.

[ȿ] Ǹ縣źĮ ܵ ϰ ʴ ¼ .

[] 1 1ȸ 1, Ļ . (CrCl<30mL/min) : Ǹ縣ź 30mg .

[] , , 󱼺, ʺ, , Ҹ.

[ݱ] Ǹ ü , Ӻ, , , ߵ~ , , Ѿ(˸Ű) 索̳ ߵ (GFR<60ml/ min/1.73m2), ٽ ȯȿ 索 ȯ, ҳ, 뵿, ȯ.

[] ׷̳ ҵ ȯ, ű ջ, , 뵿 ¸ , ļ ɱ ȯ, ߼ ˵׷, ȯ, , Ȳ4ȣ(ŸƮ) ȯ. /ü ұ, Į ߻ . û Įġ ų ִ ๰, Ƭ, ׷̵强 ҿ, OATP1B1 ü (Ŭν ), CYP3A4 , CYP3A4 , ɹٽŸƾ(Ϸεɰ ɹٽŸƾ ִ뷮 20mg/day) . ǽ, ڸ̳ ڸ꽺 .

[Ӻ] Ӻαݱ 2, ӽ Ȯ ߴ( 2~3, ¾ Ż ջ Ǵ ).

[] BCNDP ü.

 

219. Ÿ ȯ

Polystyrene Sulfonate Calcium

LPSC 30g/120ml BTL K-down suspension(۽) (219)

[] Ź (Ư ) Polystyrene sulfonate calcium Ca2+ K+ ȯϿ ȭ, ʰ 뺯 輳.

[ȿ] Į.

[] 1ȸ 1(120ml). Ź ü ϰ 30~1ð ġ. Ǵ 쿡 кθ ÷ְų (ڼ) .

[] , , Į.

[ݱ] Į, ΰ󼱱, ٹ߼, ũ̵, ̼ , ȯ ȯ, ̳ ๰ ȭ  ϵ Ż.

[] , ȭ˾, ߻ϴ ȯ. õ, Ÿ Ƿ , , ߴ óġ. û Įġ û Įġ ͸, û Įġ 5mmol/L Ϸ . ˷̴, ׳׽, Į ϴ ȭ . ٸ 汸 ๰ ȿ ҽŰǷ, 3ð Ǵ 6ð( ȯ) ΰ . ܷ ʵ .

[Ӻ] FDA C.

[] [ɱݱ] 1 ̸.

 

232. ȭ˾

Tegoprazan

BTEG50 50mg/Tab K-CAB(CJ) (232)

[] Į к(potassium-competitive acid blocker, P-CAB), 꿡 Ȱȭ ġ ʰ ϴ Proton Pump(H+/K+-ATPase) Į̿° Ͽ к .

[ȿ] ̶ ĵȯ, ̶ ĵȯ, ˾ ġ.

[] : 1 1ȸ 1, 4(̶/̶ ĵȯ) ~ 8(̶ ĵȯ, ˾), Ļ .

[] , , ȭҷ, εο, ⵵ ̷ , κ.

[ݱ] ̳ ̴̹ ι ȯ, Ÿڳ, dz, Ǻ ȯ, Ӻ .

[] ȯ, ȯ, . þƳڹ߶(Ÿ B12) , , ׳׽, տ (ŬνƮ ǽǷ ) . pH Ǵ ǰ(Ʈڳ, ö, Ƽ, ƼϺ, Ʈƿ , ) .

[Ӻ] Ȯ.

 

396.

Ertugliflozin

BERFZ 5mg(Ertugliflozin-L-pyroglutamic acid 6.477mg)/Tab Steglatro(MSD) (396)

[] SGLT2(sodium-glucose co-transporter 2) μ 翡 ġ ҽŰ, 輳 ҽŴ.

[ȿ] 2 索 ȯ Ű Ļ  ܵ Ǵ (Ʈ ܵ , Ʈ ܵ 2 Ÿ۸ƾ , Ʈΰ Ÿ۸ƾ , 索 ๰ġḦ ܵ Ÿ۸ƾ ).

[] 1 1ȸ 5mg(ʱ) ~ 15mg, Ļ ħ .

[] ı , , , Ҿ, , , εο, , ü , ü׷ , , ű , , , LDL-C , ۷κ .

[ݱ] ࿡ ɰ ι , 1, , eGFR 30ml/min /1.73m2 ̸, ȯ, ȯ, ҳ.

[] eGFR 60mL/min/1.73m2 ̸, , NYHA class III~IV ɺ, Ӻο . ű ͸(ġ , ű ҽų ִ ǰ , ȯڴ ). ¡ ͸(ü׷ , ű , , ȯ ̴ ). , Ż, ߻ ͸(ν к , ̳ , ڿ ). ı , ɰ , ȸ (ǪϿ ) ߻ .

[Ӻ] Ȯ.

 

Sugamet XR

BEVMEA 1 Evogliptin 2.5mg, Metformin 500mg(ST) (396)

BEVMEB 1 Evogliptin 5mg, Metformin 1,000mg(ST) (396)

[] Evogliptin : GLP-1 ȿ DPP-4 , GLP-1 ν к ϰ ۷ī к Ͽ . Metformin Ż ҽŰ ϽŰ ν Ŵ.

[ȿ] ۸ƾ Ʈ 2 索 ȯ Ű Ļ  Ʈ ܵ ȯ, ۸ƾ Ʈ üϴ .

[] 1 1ȸ 1~2, Ļ Բ (Max. 5mg/2,000mg/Day).

[] ȭҷ, εο, , , , , ġֿ, ߱, , , °Ű, , .

[ݱ] ߵ~ (CrCl<45ml/min), ๰ġᰡ ʿ ɺ, 缱 ϴ ˻縦 ޴ ȯ, ࿡ μ ˷ ȯ, 1, , , 索 ȥ, , ܻ , 48ð , ҷ, ƻ, , ϼüɺ, νűɺ, , , ϱ , ڿ , Ż, ȯ, Ӻ, .

[] , , ޼ 忰 ߻ . ű, û Ÿ B12 ġ ͸. 缱 ϴ ˻縦 ްų İ 븦 ϴ , 48ð ϰ 48ð ű ǸǸ ġḦ 簳. . м Ұ.

[Ӻ] Ӻαݱ 2.

 
Zemimet SR

BGEMEA 1 Gemigliptin 50mg, Metformin 500mg(LGȭ) (396)

BGEMEB 1 Gemigliptin 50mg, Metformin 1,000mg(LGȭ) (396)

[] Gemigliptin : GLP-1 ȿ DPP-4 , GLP-1 ν к ϰ ۷ī к Ͽ . Metformin Ż ҽŰ ϽŰ ν Ŵ.

[ȿ] ̱۸ƾ Ʈ 2 索 ȯ Ű Ļ  . [50/500mg, 50/1,000mg] 索 ๰ġḦ ܵ , ̱۸ƾ Ʈ üϴ . [50/1,000mg] Ʈ ܵ , Ʈΰ ҿ췹 ҿ췹ƿ .

[] 1 1ȸ 1, Ļ Բ (Max. 50mg/2,000mg/Day).

[] ȭҷ, εο, , , ̻, , , , , , ĵ, ȣ, , κ񵿿, , ٸ, , , ö̺, , չ.

[ݱ] Ǵ ٸ DPP-4 ߴ ι ȯ, ߵ ~ (CrCl<45ml/min), ๰ġᰡ ʿ ɺ, 缱 ϴ ˻縦 ޴ ȯ, 1, , , 索 ȥ, , ܻ , 48ð , ҷ, ƻ, , ϼüɺ, νűɺ, , , ϱ , ڿ , Ż, ȯ, Ӻ, .

[] , , ޼ 忰 ߻ . ű, û Ÿ B12 ġ ͸. ϴ 缱 ˻糪 İ 븦 ϴ , 48ð ϰ 48ð ű ǸǸ ġḦ 簳. . м Ұ.

[Ӻ] Ӻαݱ 2.

[] 뷮 Ǿǰ(Max. 50mg/2,000mg/Day).

 

721. X

Suclear Solution

LSUCL (1Box=2BTL) 1BTL(=177ml) Magnesium sulfate anhydrous 1.6g, Sodium sulfate anhydrous 17.5g, Potassium sulfate 3.13g(ʺ) (721)

[] ȿ ߻ϴ м  Ű 輳 Ŵ.

[ȿ] (X, ð) ˻ óġ 弼ô.

[] ˻ : ̸ 1(177ml) ȥտ⿡ ߰Ͽ ǥü(473ml) ä . 1ð ⿡ ǥü(473ml) ä 2 . ˻ : 10~12ð ˻ ° Ͽ . 1ð ǥü ä 2 .  ˻ 2ð Ǵ ǻ簡 ð ߰ 븦 Ϸ.

[] , â, , , ź꿰 , Į , , , , ̿ , , ߿(BUN) , ̿ , ũƼ , , Į , Ʈ .

[ݱ] ࿡ ȯ, Ǵ õ, ü, , , Ŵ, (eGFR<30ml/min/1.73m2), Ż, , ɺ ȯ.

[] ü ûȭ ˻ġ ̻, Ǵ ȯ, , ű , ɿ ĥ ִ ๰ , ˾ 忰, Ȱ ˾缺 忰, ݻ , Ǵ ִ ȯ. ġ . . 1ð ̳ 汸 ص .

[Ӻ] Ȯ.

 

ǰ

ڵ

Է

ǰ
(
ȸ)

ǽ

BCNDP

Cilnidipine 10mg/Tab

Cinalong
()

ü : BALDP, BBNDPA, BEFDP, BLADP4, BLCDP


 

2019. 10. 24. 

     ǰ ( 9561)